Users of screen readers cannot use a mouse to access links and other interactive elements on a web page. Likewise, users with mobility issues may use keyboard commands alone to access those interactive elements. You should ensure that, without using your mouse, you can successfully navigate your webpage and perform all functions including selecting all links. To do this, use only the tab and shift-tab keys to move around the screen and the enter or space bar to activate a link or button. If you are using a Mac, use Safari and enable this preference first: Safari > Preferences > Advanced > Check "Press Tab to highlight each item on a webpage".
If you cannot tell what link you are on when you test like this, the focus indicator has probably been deactivated, most likely with CSS. You may need to remove the code that deactivates it or use CSS to provide focus in a more creative way using a:focus.
Also notice as you try to use your webpage if you have to repeatedly tab through a lengthy set of links to get to the main section of your site. If this is the case, you might consider providing a skip link for the user. This will allow the user to go directly to the meat of the page. Here is an example of skip link code:
<body> <a href="#mainContent">Skip to main content</a> … <div id="mainContent">[page content here]</div> </body>